LONDON -- Finally, the Jacksonville Jaguars didnt let one slip away.The team that leads the NFL in surrendered leads since 2014 pulled out a gutsy 30-27 victory Sunday over the Indianapolis Colts despite conceding three fourth-quarter touchdowns to Andrew Luck and Frank Gore.Jaguars quarterback Blake Bortles held his own versus Luck, throwing for two touchdowns and running for a third. Bortles finished 19 of 33 for 207 yards and three sacks, Luck went 27 of 42 for 234 yards, two TDs, six sacks and a costly first-quarter pick.Still, Lucks three fourth-quarter touchdown drives -- the last capped by a 64-yarder to Phillip Dorsett against busted coverage -- rattled the Jaguars nerves. But Lucks fourth-and-1 pass at the Jacksonville 49 with 1:36 remaining fell from the hands of tight end Dwayne Allen to preserve the victory for under-fire Jaguars coach Gus Bradley.Man, that was exciting. Our team never stopped believing despite all that Andrew Luck threw at us, Bradley said after the Jaguars second straight win at their London second home, Wembley Stadium.Our fan base here, that atmosphere out there, was unbelievable, and our team fed off it, he said in reference to the raucous sold-out crowd of 83,764, many of whom waved yellow Jaguars (1-3) flags and raised the volume whenever Luck had the ball.The Colts (1-3) repeatedly self-destructed on offense with dropped balls and another costly Luck interception that led to Jacksonvilles opening touchdown. The Colts proved just as reckless on defense as pass interference and unnecessary roughness penalties extended three Jacksonville scoring drives.Jacksonville took a 7-0 lead after Dante Fowler Jr. shot through the middle of the line and batted Lucks pass sideways to teammate Yannick Ngakoue, who returned the interception 12 yards to the Colts 26. Bortles found Allen Robinson wide open on an inside slant for a 3-yard touchdown as Robinson easily beat Antonio Cromartie.When you have a turnover early in the game, you give up a short field and a touchdown, and 11 penalties that keep drives alive, guys have got to control their emotions, theyve got to learn when to say when, Colts coach Chuck Pagano said. Obviously we have to be better.The Jaguars led 23-6 after three quarters before the Colts mounted a tenacious comeback.The Colts first touchdown drive of the final period was aided by an end zone pass interference on safety Jonathan Cyprien. Frank Gore -- who ran 16 times for 68 yards and rose to 10th on the NFLs all-time rushing list -- punched the ball through on the next play seconds into the final period.After a Jacksonville punt, Luck led a 12-play, 78-yard touchdown drive capped by his rollout scoring toss to T.Y. Hilton alone in the right corner of the end zone to narrow the score to 23-20.The Jags didnt fold under the pressure as so often before. Bortles found Allen Hurns on a short out route that the wide receiver turned into a 42-yard touchdown. Hurns made reserve cornerback Rashaan Melvin miss, then cut inside and through the defense to put the Jaguars up 30-20 with 5:31 left.But Luck pulled the Colts back to 30-27 barely two minutes later. A coverage miscue by Jaguars rookie Jalen Ramsey left slot receiver Dorsett streaking alone to haul in the 64-yard touchdown throw.Well go back and fix what we need to fix. ... This does not feel good and it shouldnt, Luck said.JAGUARS CAN RUN: The Jaguars, who entered the game ranked as the NFLs second-worst rushing attack , got a semblance of a running game going. Yeldon carried 13 times for 68 yards and Bortles added seven scrambles for 36 yards, including a 1-yard touchdown keeper on a read-option play that put Jacksonville ahead 14-6 midway through the second quarter. Chris Ivory added eight carries for 29 yards. While nothing special, gaining 136 yards on the ground was a great improvement for a team averaging a paltry 55 per game.FOREIGN POWER: Frank Gore added to his somewhat strange status as the NFLs greatest rusher outside the United States. Sunday marked his fourth time in regular-season action on foreign soil dating back to his rookie year of 2005 in Mexico City. Gore also had strong 2010 and 2013 performances as a 49er in Londons Wembley. Adding Sundays productive numbers leaves Gore with 66 non-American carries for 264 yards and four touchdowns.MORE GORE: The running backs 68 yards on the ground raised him to 10th on the NFLs all-time rushing list at 12,293. He passed Marcus Allen, Colts all-time leading rusher Edgerrin James, and Marshall Faulk. But Gore, making his 84th straight start, most among active running backs, couldnt end the Colts most awkward streak: the longest run of any team without a 100-yard rusher. The Colts havent had one since Dec. 16, 2012, when rookie Vick Ballard reached 105 yards versus the Texans.WHATS NEXT: The Jaguars enjoy a bye week before traveling to Chicago to face the Bears. The Colts, unusually for teams making the London trip, chose not to schedule their bye after the game and will face the Bears at home Oct. 9.---AP NFL website: www.pro32.ap.org and AP NFL Twitter feed: http://twitter.com/AP-NFLCheap NBA Jerseys . Despite the cost, effort and an improved steroid test, its possible that very few -- if any -- positives will be detected, Dr. Richard Budgett told The Associated Press in an interview. "We just dont know what the results from Torino will be," Budgett said. 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Anderson might be going from breakout to heartbreak.The Denver Broncos were bracing for bad news on their starting running back, who they sent for a second opinion on his ailing right knee Wednesday.Anderson hurt it on an 11-yard run on the final play of the first quarter Monday night against Houston but returned to the game and ran 14 more times for 84 yards to spark Denvers 27-9 win.His 107-yard performance on 16 carries marked his first career 100-yard game before Halloween. Combined with rookie Devontae Bookers big night, the Broncos (5-2) finally snapped out of an offensive funk by rushing for nearly 190 yards.They left the stadium feeling really good about their new 1-2 punch in the backfield, but Anderson showed up sore Tuesday. Theyll know Thursday how much time hell miss.Were just really trying to evaluate it more than anything, coach Gary Kubiak said. He played with it. He did it early in the game. He played through it, he played really well. Actually, he was our offensive MVP. He came in really sore the day after. So, were trying to evaluate where hes at right now.With Anderson down, the Broncos would start Booker on Sunday against San Diego and Kapri Bibbs would back him up.Its kind of up to Book, how much can he handle, what kind of load can he handle? But I think he played really well the other night, Kubiak said. Kapris been chomping. So, well see where C.J.s at.Andersons injury could thwart the momentum they found in their ground game, which opened up passing lanes for their wide receivers by games end as Houston was forced to bring a safety closer to the line of scrimmage to help against the run.Booker, who ran for 83 yards and his first career TD on 17 carries against the Texans, said hes ready for a bigger role if Andersons sidelined.QQuarterback Trevor Siemian said hes comfortable with Booker, too.dddddddddddd.Book is a stud and hes been running really well for us the last couple of weeks, Siemian said. Hopefully we get C.J. back again because you would like to have two that are playing really well. But I have a lot of confidence in Book, Kapri and whoever else is back there.Also Wednesday, tight end A.J. Derby, acquired from New England for a 2017 fifth-round draft pick, practiced with his new teammates for the first time.We think he has a chance to help us really quickly, Kubiak said.Kubiak acknowledged a fifth-rounder was a steep price to pay for a backup this deep into a season, but said injuries to Virgil Green and Jeff Heuerman have stymied the Broncos and we think this kids got a bright future. He added, Id be very comfortable playing him Sunday against the Chargers.Playing behind Rob Gronkowski and Martellus Bennett, Derby played just 36 snaps. But his preseason production -- 15 receptions for 189 yards and a TD -- is roughly what the Broncos tight ends have managed this season.Obviously they have a good room back in New England. It was fun to learn from them, Derby said. ... We have a good room here, as well. Im just excited to compete with those guys.Game notes C Matt Paradis (hip), MLB Brandon Marshall (left hamstring) and NT Sylvester Williams (ankle) also missed practice as did backup C James Ferentz (non-injury). ... Marshall said he hasnt had a pulled hamstring this bad since 2008.---AP NFL website: www.pro32.ap.org and AP NFL Twitter feed: www.twitter.com/AP-NFL---Follow AP Pro Football Writer Arnie Melendrez Stapleton on Twitter: http://twitter.com/arniestapleton ' ' '